Author

N. Shoresh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

B. E. Poulsen· 2 shared D. T. Hung· 2 shared T. White· 2 shared A. Boeszoermenyi· 1 shared A. E. Clatworthy· 1 shared A. Golas· 1 shared C. Penaranda· 1 shared E. S. Lander· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

B. E. Poulsen

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Multiplexed screen identifies a Pseudomonas aeruginosa-specific small molecule targeting the outer membrane protein OprH and its interaction with LPS

T. Warrier, B. E. Poulsen, S. Barkho, J. Bagnall, K. P. Romano, T. White, X. Yu, T. Kawate, P. H. Nguyen, K. Raines, K. Ferrara, A. Golas, M. Fitzgerald, A. Boeszoermenyi, V. Kaushik, , D. T. Hung

The paper identifies a Pseudomonas aeruginosa-specific small molecule, BRD1401, that targets OprH and disrupts its interaction with LPS, increasing membrane fluidity.

bioRxiv · Mar 16, 2024 · PreprintMicrobiology

Defining the core essential genome of Pseudomonas aeruginosa

B. E. Poulsen, R. Yang, A. E. Clatworthy, T. White, S. J. Osmulski, L. Li, C. Penaranda, E. S. Lander, N. Shoresh, D. T. Hung

The paper defines the core essential genome of Pseudomonas aeruginosa by analyzing multiple strains and growth conditions using Tn-Seq and a novel statistical model, identifying 321 core essential genes.

bioRxiv · Jan 12, 2019Microbiology