Author

B. E. Poulsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

D. T. Hung· 3 shared K. P. Romano· 2 shared N. Shoresh· 2 shared P. H. Nguyen· 2 shared T. Warrier· 2 shared T. White· 2 shared A. Boeszoermenyi· 1 shared A. E. Clatworthy· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMicrobiology

D. T. Hung

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Multiplexed screen identifies a Pseudomonas aeruginosa-specific small molecule targeting the outer membrane protein OprH and its interaction with LPS

T. Warrier, B. E. Poulsen, S. Barkho, J. Bagnall, K. P. Romano, T. White, X. Yu, T. Kawate, P. H. Nguyen, K. Raines, K. Ferrara, A. Golas, M. Fitzgerald, A. Boeszoermenyi, V. Kaushik, , D. T. Hung

The paper identifies a Pseudomonas aeruginosa-specific small molecule, BRD1401, that targets OprH and disrupts its interaction with LPS, increasing membrane fluidity.

bioRxiv · Mar 16, 2024 · PreprintMicrobiology

Mutations in pmrB confer cross-resistance to the LptD inhibitor POL7080 and colistin in Pseudomonas aeruginosa

K. P. Romano, T. Warrier, B. E. Poulsen, P. H. Nguyen, A. R. Loftis, A. Saebi, B. L. Pentelute, D. T. Hung

The paper identifies mutations in pmrB conferring cross-resistance to POL7080 and colistin in Pseudomonas aeruginosa by linking resistance mechanisms to lipid A modifications.

bioRxiv · Mar 8, 2019Microbiology

Defining the core essential genome of Pseudomonas aeruginosa

B. E. Poulsen, R. Yang, A. E. Clatworthy, T. White, S. J. Osmulski, L. Li, C. Penaranda, E. S. Lander, N. Shoresh, D. T. Hung

The paper defines the core essential genome of Pseudomonas aeruginosa by analyzing multiple strains and growth conditions using Tn-Seq and a novel statistical model, identifying 321 core essential genes.

bioRxiv · Jan 12, 2019Microbiology