Author

N. Sonnenschein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1

Frequent Co-Authors

K. Jensen· 2 shared M. Herrgard· 2 shared A. Koza· 1 shared A. M. Feist· 1 shared A. S. L. Hansen· 1 shared A. T. Nielsen· 1 shared A. Toftgaard Nielsen· 1 shared B. J. Sanchez· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

K. Jensen

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Engineering of Pseudomonas putida for accelerated co-utilization of glucose and cellobiose yields aerobic overproduction of pyruvate explained by an upgraded metabolic model

D. Bujdos, B. Popelarova, D. C. Volke, P. I. Nikel, N. Sonnenschein, P. Dvorak

This study engineers P. putida EM42 to co-utilize glucose and cellobiose, leading to aerobic overproduction of pyruvate through a metabolic model constrained with proteomic and kinetic data.

bioRxiv · Jul 22, 2022Bioengineering

Genome-scale metabolic modelling of P. thermoglucosidasius NCIMB 11955 reveals metabolic bottlenecks in anaerobic metabolism.

V. Mol, M. Bennett, B. J. Sanchez, B. K. Lisowska, M. J. Herrgard, A. Toftgaard Nielsen, D. J. Leak, N. Sonnenschein

This paper develops a genome-scale metabolic model for P. thermoglucosidasius to identify metabolic bottlenecks and guide metabolic engineering.

bioRxiv · Feb 1, 2021Microbiology

Emergence of phenotypically distinct subpopulations is a factor in adaptation of recombinant Saccharomyces cerevisiae under glucose-limited conditions

N. R. Wright, T. Wulff, C. T. Workman, N. P. Ronnest, N. Sonnenschein

The paper shows that phenotypic subpopulations in recombinant yeast under glucose limitation contribute to adaptation by increasing fitness through different mechanisms.

bioRxiv · Jan 18, 2021Bioengineering

Adaptive laboratory evolution reveals general and specific chemical tolerance mechanisms and enhances biochemical production

R. Lennen, K. Jensen, E. T. Mohammed, S. Malla, R. A. Börner, K. Chekina, E. Özdemir, I. Bonde, A. Koza, J. Maury, L. E. Pedersen, L. Y. Schöning, N. Sonnenschein, B. O. Palsson, M. O. A. Sommer, , M. Herrgard

This study uses adaptive laboratory evolution to identify chemical tolerance mechanisms in E. coli and shows how pre-tolerized strains can enhance biochemical production.

bioRxiv · May 13, 2019 · PreprintMicrobiology

Cameo: A Python Library for Computer Aided Metabolic Engineering and Optimization of Cell Factories

J. Cardoso, K. Jensen, C. Lieven, A. S. L. Hansen, S. Galkina, M. E. Beber, E. Ozdemir, M. Herrgard, H. Redestig, N. Sonnenschein

Cameo provides an open-source Python platform for in silico design of cell factories, offering tools for metabolic engineering strategies and optimization.

bioRxiv · Jun 9, 2017Bioengineering