S. Malla

Full-length direct RNA sequencing uncovers stress-granule dependent RNA decay upon cellular stress

This study uses direct RNA sequencing to show that cellular stress causes widespread 5' end RNA decay linked to stress granules, independent of deadenylation or decapping.

Fish on the platter! Investigating the dietary habits of fishing cats (Prionailurus viverrinus) in the Godavari Delta, India

This study analyzes the diet of fishing cats in the Godavari Delta, finding fish as the primary prey, with seasonal variations in niche breadth and prey composition.

MmCMS: Mouse models' Consensus Molecular Subtypes of colorectal cancer

The paper develops three methods to classify mouse colorectal cancer models into human CMS subtypes, finding that pathway-level classifiers outperform gene-level ones for accurate subtype identification.

Biological misinterpretation of transcriptional signatures in tumour samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data

The paper shows that transcriptional signatures in tumour samples can be misinterpreted due to stromal influences, affecting alignment with preclinical data.

ZFP207 controls pluripotency by multiple post-transcriptional mechanisms

This study identifies ZFP207's role in maintaining mouse embryonic stem cell identity through post-transcriptional mechanisms, including alternative splicing and RNA-binding protein activity.

A Novel Stress Response Pathway Regulates Ribosome Biogenesis

This study identifies a novel stress response pathway, RiBiSR, that regulates rRNA processing and ribosome biogenesis independently of the ISR to conserve energy and maintain the nucleolus.

Adaptive laboratory evolution reveals general and specific chemical tolerance mechanisms and enhances biochemical production

This study uses adaptive laboratory evolution to identify chemical tolerance mechanisms in E. coli and shows how pre-tolerized strains can enhance biochemical production.