Quantification of ligand and mutation-induced bias in EGFR phosphorylation in direct response to ligand binding
D. Wirth, E. Ozdemir, K. Hristova
The paper quantifies ligand and mutation-induced bias in EGFR phosphorylation directly after ligand binding, showing that both factors influence RTK signaling without feedback loop contributions.
bioRxiv · Feb 13, 2023Pharmacology & Toxicology