Trypanosoma cruzi VDU deubiquitinase mediates surface protein trafficking and infectivity
N. Souza-Melo, N. Brito-Silva, A. M. Malvezzi, G. P. dos Santos, L. M. Alcantara, C. d. L. Alcantara, N. L. d. Cunha e Silva, M. Zoltner, M. C. Field, S. Schenkman
This paper identifies TcVDU as a deubiquitinase that regulates endosomal trafficking and surface protein dynamics in Trypanosoma cruzi, affecting infectivity.
bioRxiv · Apr 17, 2023 · PreprintMicrobiology