Author

M. C. Field

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 3 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:cell type annotation· 5 Research Focus:host-pathogen & immune response· 5 Research Focus:cell signaling & trafficking· 4 Assay:proteomics· 4 Research Focus:development & morphogenesis· 2 Organism:E. coli· 2 Organism:human· 2

Frequent Co-Authors

M. Zoltner· 5 shared D. Horn· 2 shared J. Lukes· 2 shared K. Zahonova· 2 shared A. M. Malvezzi· 1 shared A. M. Novak Vanclova· 1 shared A. Odom John· 1 shared A. Patel· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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5 shared papersCell Biology

M. Zoltner

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Targeted protein degradation of the CPSF complex by benzoxaboroles through sumoylation

N. Zhang, A. Samad, F. Zahedifard, R. J. Wall, D. Horn, M. Zoltner, M. C. Field

This study identifies CPSF3 as a target of benzoxaboroles in trypanosomatids, showing that BoBs induce sumoylation-dependent degradation of CPSF complex members, leading to reduced mRNA levels.

bioRxiv · Mar 11, 2024 · PreprintCell Biology

Trypanosoma cruzi VDU deubiquitinase mediates surface protein trafficking and infectivity

N. Souza-Melo, N. Brito-Silva, A. M. Malvezzi, G. P. dos Santos, L. M. Alcantara, C. d. L. Alcantara, N. L. d. Cunha e Silva, M. Zoltner, M. C. Field, S. Schenkman

This paper identifies TcVDU as a deubiquitinase that regulates endosomal trafficking and surface protein dynamics in Trypanosoma cruzi, affecting infectivity.

bioRxiv · Apr 17, 2023 · PreprintMicrobiology

Functional differentiation of Sec13 paralogs in the euglenozoan protists

D. Faktorova, K. Zahonova, C. Benz, J. B. Dacks, M. C. Field, J. Lukes

The paper identifies two Sec13 paralogs in Euglenozoa and shows they have distinct functional roles in COPII, NPC, and SEA/GATOR complexes.

bioRxiv · Nov 8, 2022 · PreprintEvolutionary Biology

Mex67 paralogs mediate division of labor in trypanosome RNA processing and export.

S. O. Obado, M. Stein, E. Hegedusova, W. Zhang, S. Hutchinson, L. Glover, Z. Paris, B. T. Chait, M. C. Field, M. P. Rout

This study identifies distinct roles for three Mex67 paralogs in trypanosome RNA processing and export, showing non-redundant functions in mRNA export and ribosome biogenesis.

bioRxiv · Jun 27, 2022 · PreprintCell Biology

The endosomal TbTpr86/TbUsp7/SkpZ (TUS) complex controls surface protein abundance in trypanosomes

K. Yamada, F. K. Yaqub, M. Zoltner, M. C. Field

The paper identifies a complex involving TbTpr86, TbUsp7, and SkpZ that regulates surface protein abundance in trypanosomes by controlling endocytosis and ubiquitination.

bioRxiv · Nov 10, 2020 · PreprintCell Biology

Instability of aquaglyceroporin (AQP) 2 contributes to drug resistance in Trypanosoma brucei

J. F. Quintana Alcala, J. A. Bueren-Calabuig, F. Zuccotto, H. de Koning, D. Horn, M. C. Field

The paper shows that instability of TbAQP2 contributes to drug resistance in Trypanosoma brucei by affecting its folding, oligomerization, and localization.

bioRxiv · Feb 22, 2020Microbiology

Modification of an atypical clathrin-independent AP-2 adaptin complex of Plasmodium falciparum reduces susceptibility to artemisinin

R. C. Henrici, R. L. Edwards, M. Zoltner, D. A. van Schalkwyk, M. N. Hart, F. Mohring, R. W. Moon, S. D. Nofal, A. Patel, C. Flueck, D. A. Baker, A. Odom John, M. C. Field, C. J. Sutherland

This study shows that modifying the AP-2 adaptin complex in Plasmodium falciparum reduces susceptibility to artemisinin, suggesting alternative mechanisms of drug resistance beyond pfkelch13 mutations.

bioRxiv · Apr 30, 2019 · PreprintMicrobiology

Proteome of the secondary plastid of Euglena gracilis reveals metabolic quirks and colourful history

A. M. Novak Vanclova, M. Zoltner, S. Kelly, P. Soukal, K. Zahonova, Z. Füssy, T. E. Ebenezer, E. Lacova Dobakova, M. Elias, J. Lukes, M. C. Field, V. Hampl

The paper identifies and annotates the plastid proteome of Euglena gracilis, revealing horizontally transferred genes and unique metabolic features.

bioRxiv · Mar 11, 2019 · PreprintEvolutionary Biology