A. H. Larsen

Membrane curvature association of amphipathic helix 8 drives constitutive GPCR endocytosis

The paper identifies amphipathic helix 8 as a driver of constitutive GPCR endocytosis through membrane curvature association.

Mg2+-dependent conformational equilibria in CorA: an integrated view on transport regulation

This study investigates the conformational dynamics of CorA, revealing Mg2+-dependent conformational equilibria and dynamic behavior through SANS, MD simulations, and NMR.

Membrane-binding mechanism of the EEA1 FYVE domain revealed by multi-scale molecular dynamics simulations

This study uses molecular dynamics simulations to reveal how the EEA1 FYVE domain binds to PI(3)P-containing membranes through a hinge mechanism involving specific interactions and flexibility.

Binding of Ca2+-Independent C2 Domains to Lipid Membranes: a Multi-Scale Molecular Dynamics Study

This study uses molecular dynamics simulations to investigate how Ca2+-independent C2 domains bind to lipid membranes, revealing binding modes and affinities for different lipid compositions.

Lipid-bound ApoE3 self-assemble into elliptical disc-shaped particles

This study examines the structural formation of lipid-bound ApoE3 particles, revealing elliptical disc shapes and differences in morphology between full-length and truncated forms.

Combining molecular dynamics simulations with small-angle X-ray and neutron scattering data to study multi-domain proteins in solution

The paper combines molecular dynamics simulations with small-angle scattering data to study multi-domain proteins, showing how refining simulations against SAXS data improves agreement with experiments.

Structure and dynamics of the central lipid pool and protein components of the bacterial holo-translocon

The paper investigates the structure and dynamics of the bacterial holo-translocon using SANS and molecular dynamics simulations, revealing a central lipid core involved in membrane protein insertion.