G. K. Christophides

This study identifies Plasmodium aquaporin 2 as essential for sporozoite production and malaria transmission, showing its localization in unique organelles and unique structural features.

This study uses a reverse genetic screen in Plasmodium berghei to identify genes essential for gametocyte-to-sporozoite development in the mosquito Anopheles coluzzii, confirming prior findings and discovering new genes involved in key stages of the parasite lifecycle.

The paper assesses the susceptibility of genetically modified Anopheles gambiae to Plasmodium falciparum infection and evaluates the impact of Scorpine expression on mosquito fitness.

This study shows that SCD1 is critical for Anopheles coluzzii female survival and reproduction after blood feeding, as its disruption leads to metabolic dysregulation and immune activation.

The paper shows that Plasmodium oocysts reduce growth under crowding and nutritional stress by entering a dormancy-like state, suggesting the need for improved methods to assess malaria transmission blocking interventions.

This study identifies PIMMS43 as a key parasite protein enabling evasion of the mosquito complement-like response and sporogonic development, suggesting it as a target for malaria transmission-blocking interventions.

This study identifies a male-specific protein disulphide isomerase essential for Plasmodium fertilization and transmission, showing it as a viable target for malaria intervention.