Author

D. Vlachou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

G. K. Christophides· 4 shared M. Giorgalli· 3 shared A. J. Bailey· 2 shared A. Jaye· 1 shared A. M. Blagborough· 1 shared A. R. Gomes· 1 shared C. V. Ukegbu· 1 shared C. Wyer· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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4 shared papersMicrobiology

G. K. Christophides

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Intracellular Plasmodium aquaporin 2 is required for sporozoite production in the mosquito vector and malaria transmission

A. J. Bailey, V. C. Ukegbu, M. Giorgalli, T. R. B. Besson, G. K. Christophides, D. Vlachou

This study identifies Plasmodium aquaporin 2 as essential for sporozoite production and malaria transmission, showing its localization in unique organelles and unique structural features.

bioRxiv · Mar 15, 2023 · PreprintMicrobiology

Reverse genetic screen identifies malaria parasite genes required for gametocyte-to-sporozoite development in its mosquito host

C. V. Ukegbu, A. R. Gomes, M. Giorgalli, M. Campos, A. J. Bailey, T. R. Besson, O. Billker, D. Vlachou, G. K. Christophides

This study uses a reverse genetic screen in Plasmodium berghei to identify genes essential for gametocyte-to-sporozoite development in the mosquito Anopheles coluzzii, confirming prior findings and discovering new genes involved in key stages of the parasite lifecycle.

bioRxiv · Mar 14, 2023 · PreprintMicrobiology

Anopheles coluzzii stearoyl-CoA desaturase is essential for adult female survival and reproduction upon blood feeding

Z. Ferdous, S. Fuchs, V. Behrends, N. Trasanidis, D. Vlachou, G. K. Christophides

This study shows that SCD1 is critical for Anopheles coluzzii female survival and reproduction after blood feeding, as its disruption leads to metabolic dysregulation and immune activation.

bioRxiv · Jun 14, 2020Microbiology

TimeTeller: a New Tool for Precision Circadian Medicine and Cancer Prognosis

D. Vlachou, G. A. Bjarnason, S. Giacchetti, F. Levi, D. A. Rand

TimeTeller assesses circadian clock dysfunction using transcriptomics data and identifies it as a prognostic biomarker in breast cancer.

bioRxiv · Mar 11, 2020 · PreprintCancer Biology

Plasmodium PIMMS43 is required for ookinete evasion of the mosquito complement-like response and sporogonic development in the oocyst

V. Ukegbu, M. Giorgalli, S. Tapanelli, L. D. Rona, A. Jaye, C. Wyer, F. Angrisano, A. M. Blagborough, G. K. Christophides, D. Vlachou

This study identifies PIMMS43 as a key parasite protein enabling evasion of the mosquito complement-like response and sporogonic development, suggesting it as a target for malaria transmission-blocking interventions.

bioRxiv · May 31, 2019 · PreprintMicrobiology