Author

Nahomie Rodríguez-Sastre

Boston University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:machine learning (classical)· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alexandra T. LioniD· 2 shared Cynthia A. BradhamiD· 2 shared Dakota Y. Hawkins· 2 shared Abigail E. DescoteauxiD· 1 shared Abigail Glick· 1 shared Andrea E. Correa· 1 shared Christopher F. Thomas· 1 shared Daniel T. ZuchiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Alexandra T. LionORCID

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2 papers

Recent·Most cited

BioinformaticsBioinformaticsPeer-reviewedApr 22, 2023

ICAT: A Novel Algorithm to Robustly Identify Cell States Following Perturbations in Single Cell Transcriptomes

Dakota Y. Hawkins, Daniel T. Zuch, James Huth…·Cynthia A. Bradham

ICAT improves identification of cell states after perturbations in single-cell RNA sequencing by using self-supervised feature weighting and control-guided clustering.

10 citations

scRNA-seqstatistical model

𝕏 PostBluesky

Developmental BiologyDevelopmental BiologyPeer-reviewedNov 8, 2022

Ethanol Exposure Perturbs Sea Urchin Development and Disrupts Developmental Timing

Nahomie Rodríguez-Sastre, Nicholas Shapiro, Dakota Y. Hawkins…·Cynthia A. Bradham

This study shows ethanol exposure disrupts skeletal patterning in sea urchin embryos by altering gene expression timing rather than affecting RA or Hh pathways.

11 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky