Distinct genetic architectures of mRNA expression and splicing QTL in the Diversity Outbred mouse population
C. Opara, Kelly A. Mitok, Christopher H. Emfinger, Katheryn L Schueler, Donnie S. Stapleton, Nancy A. Benkusky, Udaya Keerthy Gadiparthi, Kalynn Willis, Victor Ruotti, Brian S. Yandell, Mark P. Keller, Alan Attie
The paper maps eQTL, isoQTL, irQTL, and sQTL in DO mice, showing distinct genetic effects on mRNA expression and splicing, and identifies candidate genes and regulatory mechanisms.
bioRxiv · Sep 15, 2026 · PreprintGenetics