Author

Nancy Larochelle

Montreal Neurological Institute and Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Sandra Minotti· 2 shared Benoît J. GentiliD· 1 shared Caitlin S. Atkinson· 1 shared Chantelle F. SephtoniD· 1 shared Cheng-Boivin ZacharieiD· 1 shared Heather D. DurhamiD· 1 shared Javeria RizwaniD· 1 shared Josephine N. NalbantogluiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Sandra Minotti

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2 papers

Recent·Most cited

CK1α, FAM83H, and FAM83B contribute to bundling of neurofilaments and are sequestered in cellular and mice models of ARSACS

Caitlin S. Atkinson, Cheng-Boivin Zacharie, Nancy Larochelle, Sandra Minotti, Benoît J. Gentil

The paper identifies CK1α, FAM83H, and FAM83B as contributors to neurofilament bundling in ARSACS and shows their upregulation and co-localization in affected cells.

bioRxiv · Oct 1, 2024 · PreprintCell Biology

Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS

Mario Fernández Comaduran, Sandra Minotti, Suleima Jacob‐Tomas, Javeria Rizwan, Nancy Larochelle, Richard Robitaille, Chantelle F. Sephton, María Vera, Josephine N. Nalbantoglu, Heather D. Durham

This study examines the effects of HDAC inhibitors and arimoclomol on HSP expression and disease biomarkers in ALS models, finding variable responses across different ALS variants and biomarkers.

Cell Stress and Chaperones · Apr 1, 2024Peer-reviewedNeuroscience