Nancy Schwarting

An autoimmunity-associated allele of PTPN22 enhances the innate immune response to promote protection against acute coronavirus infection

This study shows that the PTPN22 1858C>T allele enhances innate immunity and protects against acute coronavirus infection by improving NK cell function.

Mutations differentially affecting the coronavirus Mac1 ADP-ribose binding and hydrolysis activities indicate that it promotes multiple stages of the viral replication cycle

This paper investigates how mutations in the coronavirus Mac1 protein affect ADP-ribose binding and hydrolysis, revealing distinct roles in viral replication stages.