Anuradha Roy

This paper investigates how mutations in the coronavirus Mac1 protein affect ADP-ribose binding and hydrolysis, revealing distinct roles in viral replication stages.

This study identifies pyrrolo-pyrimidine-based Mac1 inhibitors that inhibit MHV and SARS-CoV-2 replication, with some compounds showing IFN-dependent antiviral activity.

This study shows that mutating a conserved isoleucine in the macrodomain of MERS-CoV and SARS-CoV-2 enhances ADP-ribose binding but reduces viral replication and pathogenesis.

This study identifies bioactive compounds in American elderberry juice using metabolomics and high-throughput assays, revealing antioxidant, antiviral, and antibacterial properties.