Author

Xiaoming Zhang

Cleveland Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Aibing Liang· 1 shared Alex MilinovichiD· 1 shared Alina IvaniukiD· 1 shared Anthony R. FehriD· 1 shared Anuradha RoyiD· 1 shared Bo LiuiD· 1 shared Catherine Kerr· 1 shared Christian M. BoßelmanniD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperGenomics

Aibing Liang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mutations differentially affecting the coronavirus Mac1 ADP-ribose binding and hydrolysis activities indicate that it promotes multiple stages of the viral replication cycle

Joseph J. O’Connor, Anuradha Roy, Reem Khattabi, Catherine Kerr, Nancy Schwarting, Yousef M. O. Alhammad, Philip Gao, Xiaoming Zhang, Xufang Deng, Anthony R. Fehr

This paper investigates how mutations in the coronavirus Mac1 protein affect ADP-ribose binding and hydrolysis, revealing distinct roles in viral replication stages.

Journal of Virology · Jul 30, 2025Peer-reviewedMicrobiology

Optimized iMAP CRISPR Perturbation Illuminates Context-Specific Functions of RNA Modification Factors

Ge Wei, Zhengyu Jing, Weikai Wang, Bo Liu, Shaoshuai Mao, Junjun Lv, Xiaoming Zhang, Dingyu Cao, Ruilin Sun, Aibing Liang, Tian Chi

The paper optimizes the iMAP CRISPR platform to reduce recombination bias, profiles RNA modification factors across mouse tissues, and identifies context-specific functions with therapeutic implications.

bioRxiv · Jul 24, 2025 · PreprintGenomics

Natural language processing and expert follow-up establishes tachycardia association with CDKL5 deficiency disorder

Alina Ivaniuk, Christian M. Boßelmann, Xiaoming Zhang, Mark St John, Sara C. Taylor, Gokul Krishnaswamy, Alex Milinovich, Peter F. Aziz, Elia Pestana‐Knight, Dennis Lal

The paper uses natural language processing and phenome-wide analysis to identify tachycardia as a significant comorbidity in CDKL5 deficiency disorder.

medRxiv · Jun 24, 2023 · PreprintGenetic & Genomic Medicine