Inhibition of microtubule polymerization and dynein impairs the nuclear localization of the ependymoma-associated ZFTA-RELA fusion protein and NF-κB activation
Masaki Ishii, Naoki Suto, Ruri Kojima, Kazuaki Katakawa, Kosho Makino, Sachiko Toma-Fukai, Takeshi Tsusaka, Shunsuke Sueki, Masahiro Anada, Hirotatsu Kojima, Shinya Ohata
This study identifies microtubule and dynein inhibitors that block ZFTA-RELA nuclear localization and NF-κB activation in ependymoma cells.
Journal of Biological Chemistry · Jul 13, 2026Peer-reviewedCell Biology