Masaki Ishii

This study identifies microtubule and dynein inhibitors that block ZFTA-RELA nuclear localization and NF-κB activation in ependymoma cells.

This study identifies a putative glycan receptor in silkworms based on structural similarity to human LYSMD3 and shows that N-acetylchitohexaose induces immune priming against Pseudomonas aeruginosa infection.

This study shows that combining azole antifungals with different Cyp51 isozyme selectivities synergistically inhibits fungi with multiple Cyp51 isozymes.

This paper introduces a novel agar medium using leaf mold extract to isolate diverse soil bacteria, overcoming Bacillus dominance and enabling recovery of previously uncultured species.

The paper determines the Cryo-EM structure of PPARγ in complex with Transportin-1, revealing a non-canonical NLS recognition mechanism.

This paper develops an efficient gene targeting system in Trichophyton rubrum using a Δku80 strain and shows that Cyp51A contributes to azole drug tolerance by responding to efinaconazole.

This study identifies Cdc42 and Rac GTPase inhibition as a strategy to block hyphal elongation and virulence in Trichophyton rubrum, with EHop-016 showing promise as an antifungal lead.

This study identifies the TrPtk2-TrPma1 pathway in Trichophyton rubrum as critical for terbinafine tolerance and suggests it as a target for antifungal therapy.

This study develops a leaf mold extract agar medium that enhances the isolation of soil microbes not typically cultured in standard media, including an unidentified species.