Takeshi Tsusaka

This study identifies microtubule and dynein inhibitors that block ZFTA-RELA nuclear localization and NF-κB activation in ependymoma cells.

This study identifies the Integrated Stress Response (ISR) pathway as a regulator of aged muscle stem cell activation and regeneration, showing pharmacological ISR activation improves their function and muscle repair.

The paper shows class I HDACs can catalyze beta-hydroxybutyrylation of lysine, a reversible modification, expanding the role of HDACs beyond traditional deacetylation.

This paper identifies class I HDACs as enzymes that catalyze lysine lactylation, showing that this modification is primarily formed through enzymatic action rather than non-enzymatic pathways.