Nasrin Mortazavi

In vivo modulation of locus coeruleus activity by light

This study shows light modulates locus coeruleus (LC) activity in an emotion-dependent manner, with higher illuminance dampening responses to negative stimuli and enhancing neutral ones.

Regional Hypothalamic Responses to Light Vary Across Developmental Stages but Remain Stable with Time of Day

This study examines how light affects hypothalamic activity in adolescents and young adults across different times of day, finding stable regional responses with developmental differences in magnitude.

Pooling quantitative MRI data: A multi-protocol study of healthy subcortical ageing

This study evaluates how protocol and hardware differences affect pooling quantitative MRI data across sites in healthy aging studies, finding both benefits and drawbacks for analysis outcomes.

Age-related differences in the association between REM sleep and the polygenic risk for Parkinson's disease

The paper examines how polygenic risk for Parkinson's disease relates to REM sleep metrics in young and late-midlife individuals, finding age-dependent associations.

Regional activity within the human amygdala varies with season, mood and illuminance

This study investigates how seasonal changes, mood, and light exposure affect regional activity in the human amygdala using fMRI.

Sleep arousals are associated with the polygenic risk for developing Alzheimer's disease and with cognitive decline in healthy late middle-aged individuals

This study links specific sleep arousal subtypes to polygenic risk for Alzheimer's disease and cognitive decline in late middle-aged individuals.

The crosstalk between the anterior hypothalamus and the locus coeruleus during wakefulness is associated with low frequency oscillations power during sleep

This study examines the relationship between effective connectivity between the locus coeruleus and hypothalamus subregions and sleep electrophysiology in young and older adults.

Light Impact on Thalamo-Cortical Connectivity During a Cognitive Task Depends on Time of Day and is Different in Teenagers

This study shows that light affects thalamo-cortical connectivity during a cognitive task, with differences based on time of day and age group.

REM sleep quality is associated with balanced tonic activity of the locus coeruleus during wakefulness

The paper investigates the relationship between locus coeruleus (LC) activity during wakefulness and REM sleep quality in humans, finding task-dependent associations.

Regional response to light illuminance across the human hypothalamus

This study investigates how varying light levels affect different regions of the human hypothalamus during cognitive tasks, finding distinct activity patterns linked to task performance.

Impact of light on task-evoked pupil responses during cognitive tasks.

This study examines how different light levels affect task-evoked pupil responses during cognitive tasks, finding that higher light levels increase pupil dilation in response to auditory stimuli.

Impact of repeated short light exposures on sustained pupil responses in an fMRI environment

The paper investigates how repeated short light exposures affect sustained pupil responses during different cognitive tasks, finding that higher melanopic irradiance increases pupil responses and that task context influences variability.

Light modulates task-dependent thalamo-cortical connectivity during an auditory attentional task

This study shows blue-enriched light enhances thalamo-cortical connectivity during an auditory attention task, supporting its role in modulating cognitive activity.

In vivo Locus Coeruleus activity while awake is associated with REM sleep quality in healthy older individuals

This study finds that higher locus coeruleus activity during wakefulness in older adults is linked to worse sleep quality and reduced theta band power during REM sleep.

MRI-assessed locus coeruleus contrast and functional response are not associated in young and late middle-aged individuals

The paper investigates the relationship between structural and functional characteristics of the locus coeruleus in young and late middle-aged individuals using MRI and finds no association between LC contrast and functional response.