Puneet Talwar

COFITAGE provides a longitudinal neuroimaging dataset for studying brain aging, integrating MRI, PET, genetics, and cognitive assessments across 50-70 year olds.

This study shows light modulates locus coeruleus (LC) activity in an emotion-dependent manner, with higher illuminance dampening responses to negative stimuli and enhancing neutral ones.

This study examines how light affects hypothalamic activity in adolescents and young adults across different times of day, finding stable regional responses with developmental differences in magnitude.

This study evaluates how protocol and hardware differences affect pooling quantitative MRI data across sites in healthy aging studies, finding both benefits and drawbacks for analysis outcomes.

The paper examines how polygenic risk for Parkinson's disease relates to REM sleep metrics in young and late-midlife individuals, finding age-dependent associations.

This study investigates how seasonal changes, mood, and light exposure affect regional activity in the human amygdala using fMRI.

This study links specific sleep arousal subtypes to polygenic risk for Alzheimer's disease and cognitive decline in late middle-aged individuals.

This study examines the relationship between effective connectivity between the locus coeruleus and hypothalamus subregions and sleep electrophysiology in young and older adults.

This study shows that light affects thalamo-cortical connectivity during a cognitive task, with differences based on time of day and age group.

The paper investigates the relationship between locus coeruleus (LC) activity during wakefulness and REM sleep quality in humans, finding task-dependent associations.

This study investigates how varying light levels affect different regions of the human hypothalamus during cognitive tasks, finding distinct activity patterns linked to task performance.

The paper investigates how repeated short light exposures affect sustained pupil responses during different cognitive tasks, finding that higher melanopic irradiance increases pupil responses and that task context influences variability.

This study shows blue-enriched light enhances thalamo-cortical connectivity during an auditory attention task, supporting its role in modulating cognitive activity.

The paper investigates the association between brainstem myelin content and sleep parameters in healthy young men, finding significant links between myelin integrity and sleep quality metrics.

This study finds that higher locus coeruleus activity during wakefulness in older adults is linked to worse sleep quality and reduced theta band power during REM sleep.

The paper investigates the relationship between structural and functional characteristics of the locus coeruleus in young and late middle-aged individuals using MRI and finds no association between LC contrast and functional response.