Cytosolic DNA structures produced by mismatch-repair deficiency coordinate anti-tumor immunity in colorectal cancer
Shayla R. Mosley, Natalie Lapa, Afshin Namdar, Thomas E. Catley, Felix Meier‐Stephenson, Courtney Mowat, Pinzhang Gao, Xuejun Sun, Vanessa Meier‐Stephenson, Alice L. B. Pyne, Kristi Baker
The paper identifies cytosolic DNA structures in MSI CRC that enhance STING activation and anti-tumor immunity, suggesting potential for improved DNA-based therapies.
Cell Reports · Feb 19, 2026Peer-reviewedCancer Biology