Author

Natalie Lipieta

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Allison R. HickmaniD· 1 shared Bryan J. VentersiD· 1 shared Carolina P. LiniD· 1 shared Chao LüiD· 1 shared Daniel N. WeinbergiD· 1 shared Danielle N MaryanskiiD· 1 shared Hailey F. TayloriD· 1 shared Hiroshi NakagawaiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Allison R. HickmanORCID

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1 paper

Recent·Most cited

Cancer-associated DNA Hypermethylation of Polycomb Targets Requires DNMT3A Dual Recognition of Histone H2AK119 Ubiquitination and the Nucleosome Acidic Patch

Kristjan H. Gretarsson, Stephen Abini-Agbomson, Susan L. Gloor, Daniel N. Weinberg, Jamie L McCuiston, Vishnu U. Sunitha Kumary, Allison R. Hickman, Varun Sahu, Rachel Lee, Xinjing Xu, Natalie Lipieta, Samuel P. Flashner, Oluwatobi A. Adeleke, Irina K Popova, Hailey F. Taylor, , Chao Lü

The paper identifies a critical binding interface in DNMT3A1 that facilitates DNA hypermethylation at Polycomb target genes by recognizing H2AK119Ub and the nucleosome acidic patch.

Science Advances · Aug 28, 2024Peer-reviewedCancer Biology