Author
EpiCypher (United States)ORCID 0009-0003-3845-9458Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Alexander S Lee, Nickolas P. Fisher, Matthew R. Marunde…·Neil L. Kelleher
This paper introduces Nuc-MS, a method to directly analyze chromatin reader-nucleosome interactions by disassembling complexes and identifying histone proteoforms involved in binding.
Matthew R. Marunde, Irina K Popova, Nathan W Hall…·Jonathan M. Burg
The paper investigates how nucleosome context influences chromatin reader binding preferences using biochemical and genomic approaches, revealing that multivalent engagement often has regulatory effects beyond simple additivity.
Kristjan H. Gretarsson, Stephen Abini-Agbomson, Susan L. Gloor…·Chao Lü
The paper identifies a critical binding interface in DNMT3A1 that facilitates DNA hypermethylation at Polycomb target genes by recognizing H2AK119Ub and the nucleosome acidic patch.
Matthew R. Marunde, Harrison A. Fuchs, Jonathan M. Burg…·Catherine A. Musselman
The paper shows that histone reader domains interact with PTMs in a nucleosome-dependent manner, necessitating a refinement of the histone code concept to the nucleosome level.