HOCl Forms Lipid N-Chloramines in Cell Membranes of Bacteria and Immune Cells
Lisa R. Knoke, Sara Abad Herrera, Sascha Heinrich, Frank M.L. Peeters, Natalie Lupilov, Julia Elisabeth Bandow, Thomas Günther Pomorski
The paper shows HOCl forms lipid N-chloramines in bacterial and immune cell membranes, which oxidize proteins and are neutralized by glutathione, suggesting a role in inflammation and immune response.
Free Radical Biology and Medicine · Sep 12, 2024Peer-reviewedMicrobiology