Author

Natarajan Amarnath

Fred and Pamela Buffett Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

Chiemerie Azubuogu· 1 shared Corinna ProbstiD· 1 shared Gabriele MeloniiD· 1 shared Julia A. CriccoiD· 1 shared Kamal Nain Singh· 1 shared Kathryn A. ConradiD· 1 shared Madujika A Horadigala Gamage· 1 shared Marı́a G. MediavillaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Chiemerie Azubuogu

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1 paper

Recent·Most cited

A First-In-Class Broad Spectrum Inhibitor of Copper Exporting P1B-type ATPases

Vinit Shanbhag, Samuel Anakpeba-Dinguyella, Nikita Gudekar, Kathryn A. Conrad, Chiemerie Azubuogu, Corinna Probst, Martina Ralle, Marı́a G. Mediavilla, Julia A. Cricco, Natalie M. Garza, Vishal M. Gohil, Scott C. Peck, Siddhartha Kumar, Natarajan Amarnath, Madujika A Horadigala Gamage, , Michael J. Petris

This paper identifies MKV3 as the first small-molecule inhibitor of Cu+-transporting P1B-type ATPases, showing broad activity across species and defining a conserved Cu+ entry pocket for drug development.

bioRxiv · Jan 24, 2026 · PreprintCell Biology