Integration of Thermal Proteome Profiling with phosphoproteomic and transcriptomic data via mechanistic network models decodes the molecular response to PARP inhibition
Mira Lea Burtscher, Stephan Gade, Martín Garrido‐Rodríguez, Ania Rutkowska, Thilo Werner, H. Christian Eberl, Massimo Petretich, Natascha Knopf, Katharina Zirngibl, Paola Grandi, Giovanna Bergamini, Marcus Bantscheff, Maria Faelth-Savitski, Julio Sáez-Rodríguez
The paper integrates Thermal Proteome Profiling with phosphoproteomic and transcriptomic data using network models to uncover molecular responses to PARP inhibition in ovarian cancer.
bioRxiv · Aug 15, 2023 · PreprintSystems Biology