Author

H. Christian Eberl

GlaxoSmithKline (Germany)ORCID 0000-0002-4159-5958Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Marcus BantscheffiD· 2 shared Ania RutkowskaiD· 1 shared Bernhard KüsteriD· 1 shared Daniel C. SéviniD· 1 shared Giovanna BergaminiiD· 1 shared Johanna KorbeńiD· 1 shared Julio Sáez-RodrígueziD· 1 shared Katharina ZirngibliD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersPharmacology & Toxicology

Marcus BantscheffORCID

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2 papers

Recent·Most cited

Pharmacoproteomic profiling identifies secreted markers for aberrant drug action

Sascha Knecht, Mathias Kalxdorf, Johanna Korbeń, Toby Mathieson, Daniel C. Sévin, Bernhard Küster, Richard Kasprowicz, Melanie Z. Sakatis, H. Christian Eberl, Marcus Bantscheff

The paper uses proteomics to identify secreted markers linked to drug-induced liver injury and adverse drug reactions by analyzing the secretome of hepatocytes exposed to various drugs.

bioRxiv · Oct 16, 2024 · PreprintPharmacology & Toxicology

Integration of Thermal Proteome Profiling with phosphoproteomic and transcriptomic data via mechanistic network models decodes the molecular response to PARP inhibition

Mira Lea Burtscher, Stephan Gade, Martín Garrido‐Rodríguez, Ania Rutkowska, Thilo Werner, H. Christian Eberl, Massimo Petretich, Natascha Knopf, Katharina Zirngibl, Paola Grandi, Giovanna Bergamini, Marcus Bantscheff, Maria Faelth-Savitski, Julio Sáez-Rodríguez

The paper integrates Thermal Proteome Profiling with phosphoproteomic and transcriptomic data using network models to uncover molecular responses to PARP inhibition in ovarian cancer.

bioRxiv · Aug 15, 2023 · PreprintSystems Biology