Author

Nathanael Ashby

George Washington University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Inhee ChungiD· 2 shared Ananya Gottumukkala· 1 shared Christine B. Teal· 1 shared Kangsun Yun· 1 shared Maxine Rubin· 1 shared Patricia S. LathamiD· 1 shared Robert G. HawleyiD· 1 shared Sana O. Tabbara· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Inhee ChungORCID

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2 papers

Recent·Most cited

Log-linear scaling of TRPV4-KCNN4 transcripts tunes ROCK-dependent mechanotransduction in a DCIS progression model

Nathanael Ashby, Maxine Rubin, Robert G. Hawley, Inhee Chung

The paper shows TRPV4 and KCNN4 mRNA levels log-linearly scale with motility in a DCIS progression model under stress, while bulk TRPV4 protein does not correlate with motility.

bioRxiv · Feb 20, 2026 · PreprintCell Biology

Cell crowding activates pro-invasive mechanotransduction pathway in high-grade DCIS via TRPV4 inhibition and cell volume reduction

Xiangning Bu, Nathanael Ashby, Teresa Vitali, Sulgi Lee, Ananya Gottumukkala, Kangsun Yun, Sana O. Tabbara, Patricia S. Latham, Christine B. Teal, Inhee Chung

This study shows cell crowding promotes invasion in high-grade DCIS by reducing cell volume through TRPV4 inhibition and mechanotransduction.

eLife · Sep 26, 2024Peer-reviewedCell Biology