Sub-therapeutic Concentrations of Antibiotics Induce Prophage-driven Superinfection Exclusion and Fitness Cost in Pseudomonas aeruginosa
Michael J Bucher, Cristian P Puente, Naveen Sehdev, Daniel M. Czyż
This study shows sub-therapeutic antibiotics in Pseudomonas aeruginosa induce prophage activation, leading to reduced virulence through superinfection exclusion and fitness costs.
bioRxiv · Nov 20, 2024 · PreprintMicrobiology