Author

Michael J Bucher

University of FloridaORCID 0009-0005-1296-6288Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Assay:clinical cohort / trial· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Daniel M. CzyżiD· 2 shared Anton Yariv PelegiD· 1 shared Bradley J. GardineriD· 1 shared C. Rees· 1 shared Cristian P Puente· 1 shared D. KeatingiD· 1 shared Denis KorneeviD· 1 shared Devang M. PateliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

Daniel M. CzyżORCID

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3 papers

Recent·Most cited

MicrobiologyNature MedicinePeer-reviewedApr 24, 2026

Mechanistic insights and clinical implications of cross-reactive anti-prophage antibodies and bacterial heteroresistance on phage therapeutic failure

Fernando L. Gordillo Altamirano, Dinesh Subedi, Mariel Beiers…·Anton Yariv Peleg

The paper identifies pre-existing anti-prophage antibodies and bacterial heteroresistance as factors contributing to phage therapy failure in a patient with chronic infection.

8 citationstop 1%

humanclinical cohort / trial

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MicrobiologybioRxivPreprintApr 3, 2025

High-content assessment of Pseudomonas aeruginosa bacteriophage efficacy reveals host genetic factors involved in phage specificity

Garrett L. Ellward, Michael J Bucher, Yuting Zhai…·Daniel M. Czyż

The paper develops a high-content screen to identify effective Pseudomonas aeruginosa phages and identifies host genes influencing phage specificity.

DOI 10.1101/2025.04.03.646983

humanmouse

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MicrobiologybioRxivPreprintNov 20, 2024

Sub-therapeutic Concentrations of Antibiotics Induce Prophage-driven Superinfection Exclusion and Fitness Cost in Pseudomonas aeruginosa

Michael J Bucher, Cristian P Puente, Naveen Sehdev, Daniel M. Czyż

This study shows sub-therapeutic antibiotics in Pseudomonas aeruginosa induce prophage activation, leading to reduced virulence through superinfection exclusion and fitness costs.

1 citation

bacteria (other)experimental assay

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