Systemic Nanobubbles Enable Ultrasound-Guided STING Immunotherapy in Breast Cancer
Nazia Hafeez, Sina Khorsandi, Ruoqi Gao, Aman Khalid, Shariq Ali, Tara Movaghar, Shea Garland, Caroline de Gracia Lux, Jacques Lux
This paper develops SONATA, a nanobubble-based ultrasound-guided immunotherapy that activates the STING pathway in breast cancer, showing tumor growth inhibition and improved survival in mice.
bioRxiv · Aug 19, 2026 · PreprintBioengineering