Author

Ruoqi Gao

Northwestern UniversityORCID 0000-0001-9490-9677Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Marc P. ForrestiD· 3 shared María Dolores Martin‐de‐SaavedraiD· 3 shared Peter PenzesiD· 3 shared Jeffrey N. SavasiD· 2 shared Marc Dos SantosiD· 2 shared Sehyoun YooniD· 2 shared Alfred L. GeorgeiD· 1 shared Aman KhalidiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersNeuroscience

Marc P. ForrestORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Systemic Nanobubbles Enable Ultrasound-Guided STING Immunotherapy in Breast Cancer

Nazia Hafeez, Sina Khorsandi, Ruoqi Gao, Aman Khalid, Shariq Ali, Tara Movaghar, Shea Garland, Caroline de Gracia Lux, Jacques Lux

This paper develops SONATA, a nanobubble-based ultrasound-guided immunotherapy that activates the STING pathway in breast cancer, showing tumor growth inhibition and improved survival in mice.

bioRxiv · Aug 19, 2026 · PreprintBioengineering

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yizhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, María Dolores Martin‐de‐Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Mark S. LeDoux, Jennifer A. Kearney, , Peter Penzes

This study identifies PRRT2 as a key hub in an epilepsy network disrupted by 16p11.2 duplication and shows its correction rescues multiple neuropsychiatric and seizure-related phenotypes in mice.

Nature Communications · Feb 17, 2023Peer-reviewedNeuroscience

CNTNAP2 is targeted to endosomes by the polarity protein Par3

Ruoqi Gao, Christopher P. Pratt, Sehyoun Yoon, María Dolores Martin‐de‐Saavedra, Marc P. Forrest, Peter Penzes

This study identifies Par3 as a binding partner of CNTNAP2, showing that Par3 localizes CNTNAP2 to endosomes and stabilizes its presence there.

European Journal of Neuroscience · Nov 15, 2019Peer-reviewedNeuroscience

CNTNAP2 ectodomain, detected in neuronal and CSF sheddomes, modulates Ca2+ dynamics and network synchrony

María Dolores Martin‐de‐Saavedra, Marc Dos Santos, Olga Varea, Benjamin P. Spielman, Ruoqi Gao, Marc P. Forrest, Kristoffer Myczek, Natalia Khalatyan, Elizabeth Hall, Antonio Sanz-Clemente, Davide Comoletti, Stefan F. Lichtenthaler, Jeffrey N. Savas, Peter Penzes

bioRxiv · Apr 10, 2019 · PreprintNeuroscience