Rapid Screening and Validation of Intracellularly Active Antimycobacterial Compounds with Efficacy in Cellular and Murine Tuberculosis Models
Mahima Madan, Kanika Bisht, Neetu Sehrawat, Vivek Rao
This paper validates a THP-1 macrophage model with Mycobacterium marinum for rapid screening of intracellular antimycobacterial compounds, identifying phenothiazines as effective adjuncts to TB therapy.
bioRxiv · Sep 23, 2025 · PreprintMicrobiology