Conserved Fibroblast Subsets Drive Shared Fibrotic Mechanisms in Osteoarthritis Synovium and Systemic Sclerosis Skin
Aanya Mohan, Michael D. Newton, Neil Bhate, Alexandra A. Khmelevskaya, Tareq M. Hanna, Edward F. DiCarlo, Caroline Ospelt, Dana E. Orange, John Varga, Tristan Maerz
This study identifies conserved fibroblast subsets and fibrotic mechanisms in osteoarthritis and systemic sclerosis using single-cell RNA-seq and spatial transcriptomics.
bioRxiv · Oct 6, 2026 · PreprintCell Biology