Aanya Mohan

This study identifies PIEZO1 as a critical mediator of myofibroblast activation and fibrosis in post-traumatic osteoarthritis through mechanosensing mechanisms.

This study identifies conserved fibroblast subsets and fibrotic mechanisms in osteoarthritis and systemic sclerosis using single-cell RNA-seq and spatial transcriptomics.

This study identifies decorin-mediated extracellular matrix stabilization as a key factor in maintaining cartilage integrity during aging, showing its role in preventing age-associated osteoarthritis.

This study shows that TSP2 deficiency leads to increased joint inflammation and worsened osteoarthritis after injury, suggesting TSP2's role in joint homeostasis.

This paper develops a sample processing pipeline for spatial transcriptomics of murine musculoskeletal tissues, achieving high-quality transcript detection across multiple tissue types using the Xenium Prime 5K platform.

This study shows CXCL16 drives synovial inflammation and joint pain through CXCR6, suggesting it as a target for treating post-traumatic osteoarthritis.