Erica L. Scheller

This study maps and characterizes Schwann cells in bone, revealing differences in maturity and distribution between neural crest- and mesoderm-derived bone compartments.

This paper describes a protocol using microCT scans and Dragonfly for quantifying bone remodeling in rodents over time without coding expertise.

This study uses spatial transcriptomics to identify Slc13a5 as a regulator of bone mechanoadaptation, showing its role in mineralization and resorption under mechanical loading.

The paper identifies a catecholamine-independent lipolysis pathway activated by hypoglycemia and hypoinsulinemia that enables catabolism of stable adipose tissues.

This study tracks the temporal changes in chemokine production and neurovascular invasion in mouse intervertebral discs during degeneration following injury.

The paper identifies FGF1 signaling as a sensorineural-skeletal interaction that impairs bone healing in critical-sized defects by promoting osteoprogenitor proliferation and inhibiting differentiation.

The paper identifies six genes with causal roles in aging by analyzing gene expression across species and testing their effects on lifespan in C. elegans.

This study shows that maternal high-fat/high-sugar diet affects craniofacial and dental morphology in adult offspring mice, with sex-specific and generation-persistent skeletal effects in females.

This study shows that VEGFA drives neurovascular invasion in degenerating intervertebral discs and contributes to chronic low back pain, with its inhibition preventing pain behaviors.

This study quantifies SARM1 activity in human PBMCs using agonists and inhibitors, showing dose-dependent cAPDR increases and potential for clinical readouts.

This paper identifies CCN3 as a brain-derived hormone that promotes bone mass in lactating females by compensating for estrogen loss and supporting skeletal stem cells.

This paper maps sympathetic adrenergic and sensory peptidergic axons in mouse limb bones to identify region-specific innervation patterns related to bone pain, repair, and homeostasis.