A role for selective autophagy of the ER in gametogenic rejuvenation revealed by microfluidics-based lifespan profiling
Silvan Spiri, Tina Lynn Sing, Nhi Phung, Jay S Goodman, Elçin Ünal, Gloria Ann Brar
The paper introduces a high-throughput microfluidic assay to study gametogenic rejuvenation in yeast and identifies Atg39 and Atg40 as molecular determinants of lifespan resetting.
bioRxiv · Oct 7, 2025 · PreprintMolecular Biology