BiophysicsbioRxivPreprint
A single residue determines regulation of TRPV1 by phosphoinositides
Benjamin He, Prateeti Varanasi, Nia M Barkum…·Eric N. Senning
This paper identifies a single residue, H410, that determines how TRPV1 interacts with phosphoinositides, revealing a two-site binding mechanism for PI(4,5)P2 regulation.
DOI 10.1101/2025.10.15.682641