Author

Nicholas Doak

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Allison L. DidychukiD· 1 shared Jimin WangiD· 1 shared Pankaj Madheshiya· 1 shared Shannon HenryiD· 1 shared Shaogeng TangiD· 1 shared Taylor R. GierkeiD· 1 shared Xinyu CheniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Allison L. DidychukORCID

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1 paper

Recent·Most cited

Kaposi's Sarcoma-associated herpesvirus uses a novel protein fold to hijack RNA Polymerase II for viral late gene transcription

Pankaj Madheshiya, Shannon Henry, Xinyu Chen, Nicholas Doak, Taylor R. Gierke, Shaogeng Tang, Jimin Wang, Allison L. Didychuk

This study identifies a novel protein fold in KSHV ORF24 that enables direct binding to RNAPII CTD, facilitating viral late gene transcription through structural mimicry of a host transcription factor.

bioRxiv · Jun 29, 2026 · PreprintMicrobiology