MicrobiologybioRxivPreprint
Kaposi's Sarcoma-associated herpesvirus uses a novel protein fold to hijack RNA Polymerase II for viral late gene transcription
Pankaj Madheshiya, Shannon Henry, Xinyu Chen…·Allison L. Didychuk
This study identifies a novel protein fold in KSHV ORF24 that enables direct binding to RNAPII CTD, facilitating viral late gene transcription through structural mimicry of a host transcription factor.
DOI 10.64898/2026.06.29.734287