Author

Pankaj Madheshiya

Yale University

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Biology Disciplines

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Microbiology· 1

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Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Allison L. DidychukiD· 1 shared Jimin WangiD· 1 shared Nicholas Doak· 1 shared Shannon HenryiD· 1 shared Shaogeng TangiD· 1 shared Taylor R. GierkeiD· 1 shared Xinyu CheniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Allison L. DidychukORCID

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1 paper

Recent·Most cited

MicrobiologybioRxivPreprintJun 29, 2026

Kaposi's Sarcoma-associated herpesvirus uses a novel protein fold to hijack RNA Polymerase II for viral late gene transcription

Pankaj Madheshiya, Shannon Henry, Xinyu Chen…·Allison L. Didychuk

This study identifies a novel protein fold in KSHV ORF24 that enables direct binding to RNAPII CTD, facilitating viral late gene transcription through structural mimicry of a host transcription factor.

DOI 10.64898/2026.06.29.734287

humanstructural biology

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