Characterizing Molecular and Synaptic Signatures in Mouse Models of Late-Onset Alzheimer's Disease Independent of Amyloid and Tau Pathology
Kevin P. Kotredes, Ravi S. Pandey, Scott A. Persohn, Kierra Elderidge, Charles P. Burton, Ethan W. Miner, Kathryn A. Haynes, Diogo Francisco da Silva dos Santos, Sean‐Paul Gerard Williams, Nicholas Heaton, Cynthia M. Ingraham, Christopher D Lloyd, Dylan T. Garceau, Rita O’Rourke, Sarah Herrick, , Adrian L. Oblak
This study characterizes molecular and synaptic changes in a mouse model of late-onset Alzheimer's disease under different dietary conditions, showing age-related brain volume loss and cognitive deficits.
Alzheimer s & Dementia · May 12, 2024Peer-reviewedNeuroscience