Author

Diogo Francisco da Silva dos Santos

University of PittsburghORCID 0000-0003-3306-2147Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adrian L. OblakiD· 1 shared Bradley Kenneth TayloriD· 1 shared Bruce T. LambiD· 1 shared Charles P. Burton· 1 shared Christopher D Lloyd· 1 shared Claudia Rangel‐BarajasiD· 1 shared Cynthia M. Ingraham· 1 shared Dylan T. Garceau· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Adrian L. OblakORCID

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2 papers

Recent·Most cited

Characterizing Molecular and Synaptic Signatures in Mouse Models of Late-Onset Alzheimer's Disease Independent of Amyloid and Tau Pathology

Kevin P. Kotredes, Ravi S. Pandey, Scott A. Persohn, Kierra Elderidge, Charles P. Burton, Ethan W. Miner, Kathryn A. Haynes, Diogo Francisco da Silva dos Santos, Sean‐Paul Gerard Williams, Nicholas Heaton, Cynthia M. Ingraham, Christopher D Lloyd, Dylan T. Garceau, Rita O’Rourke, Sarah Herrick, , Adrian L. Oblak

This study characterizes molecular and synaptic changes in a mouse model of late-onset Alzheimer's disease under different dietary conditions, showing age-related brain volume loss and cognitive deficits.

Alzheimer s & Dementia · May 12, 2024Peer-reviewedNeuroscience

Endogenous μ-opioid - neuropeptide Y Y1 receptor synergy silences chronic postoperative pain

Tyler S. Nelson, Diogo Francisco da Silva dos Santos, Pranav Prasoon, Margaret Gralinski, Heather N. Allen, Bradley Kenneth Taylor

The paper shows that MOR and Y1R receptor synergy in spinal cord interneurons reduces postoperative hyperalgesia and ongoing pain after surgery.

PNAS Nexus · Aug 1, 2023Peer-reviewedNeuroscience