Author

Kathryn A. Haynes

University of PittsburghORCID 0000-0002-5064-6905Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:imaging· 1

Frequent Co-Authors

Adrian L. OblakiD· 2 shared Bruce T. LambiD· 2 shared Gregory W. CarteriD· 2 shared Michael SasneriD· 2 shared Paul R. TerritoiD· 2 shared Ravi S. PandeyiD· 2 shared Stacey J. Sukoff RizzoiD· 2 shared Ankit Nagar· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersNeuroscience

Adrian L. OblakORCID

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2 papers

Recent·Most cited

Molecular mechanisms underlying amyloid lowering by aducanumab: differential and comparative effects of sex and IgG reveal the post-treatment disease brain

Kathryn A. Haynes, Ravi S. Pandey, Emma H. Doud, Zackary A. Cope, Gabriela J. Little, Sean-Paul Williams, Umesh Nepali, Sara K. Quinney, Ankit Nagar, Nitin Charbe, Lais Da Silva, Jeffrey L. Dage, Duc M. Duong, Nicholas T. Seyfried, Michael Sasner, , Stacey J. Sukoff Rizzo

This study examines the molecular effects of aducanumab treatment in 5XFAD mice, revealing sex-dependent and IgG-mediated changes in amyloid and associated pathways.

bioRxiv · Jun 21, 2026 · PreprintNeuroscience

Characterizing Molecular and Synaptic Signatures in Mouse Models of Late-Onset Alzheimer's Disease Independent of Amyloid and Tau Pathology

Kevin P. Kotredes, Ravi S. Pandey, Scott A. Persohn, Kierra Elderidge, Charles P. Burton, Ethan W. Miner, Kathryn A. Haynes, Diogo Francisco da Silva dos Santos, Sean‐Paul Gerard Williams, Nicholas Heaton, Cynthia M. Ingraham, Christopher D Lloyd, Dylan T. Garceau, Rita O’Rourke, Sarah Herrick, , Adrian L. Oblak

This study characterizes molecular and synaptic changes in a mouse model of late-onset Alzheimer's disease under different dietary conditions, showing age-related brain volume loss and cognitive deficits.

Alzheimer s & Dementia · May 12, 2024Peer-reviewedNeuroscience