Molecular BiologybioRxivPreprint
An integrated DNA interactome and transcriptome profiling reveals a PU.1/enhancer RNA-mediated Feed-forward Regulatory Loop Regulating monocyte/macrophage development and innate immune functions
A. S. M. Waliullah, Kevin Qiu, Barbara Dziegielewska…·Bon Q. Trinh
This study identifies a PU.1/LOUP feed-forward regulatory loop that promotes monocyte/macrophage differentiation and innate immune functions through enhancer RNA-mediated mechanisms.