Author

Kevin Qiu

University of VirginiaORCID 0009-0008-0168-7306Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Bon Q. TrinhiD· 2 shared Daniel Geoffrey TeneniD· 2 shared Leran WangiD· 2 shared A. S. M. WaliullahiD· 1 shared Adam N. GoldfarbiD· 1 shared Aiying ZhangiD· 1 shared Alev ErişiriD· 1 shared Allison Tucker· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

Bon Q. TrinhORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 17, 2025

Modeling Alzheimer's Disease with APOE4 Neuron-Glial Brain Assembloids Reveals IGFBPs as Therapeutic Targets

Eliana Sherman, Kevin Qiu, Rebecca Roberts…·the Alzheimer’s Disease Neuroimaging Initiative

The paper develops a 3D brain assembloid model to study Alzheimer's disease progression and identifies IGFBP pathways as therapeutic targets in APOE4 carriers.

DOI 10.1101/2025.10.17.683162

humanscRNA-seq

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Molecular BiologybioRxivPreprintFeb 19, 2025

An integrated DNA interactome and transcriptome profiling reveals a PU.1/enhancer RNA-mediated Feed-forward Regulatory Loop Regulating monocyte/macrophage development and innate immune functions

A. S. M. Waliullah, Kevin Qiu, Barbara Dziegielewska…·Bon Q. Trinh

This study identifies a PU.1/LOUP feed-forward regulatory loop that promotes monocyte/macrophage differentiation and innate immune functions through enhancer RNA-mediated mechanisms.

DOI 10.1101/2025.02.19.638695

humanChIP-seq

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GeneticsbioRxivPreprintJan 1, 2024

Chromatin structure and 3D architecture define differential functions of PU.1 cis regulatory elements in human blood cell lineages

Kevin Qiu, Duc Vu, Leran Wang…·Bon Q. Trinh

The paper identifies PU.1 cis-regulatory elements in human blood cell lineages and shows how chromatin structure and 3D architecture influence their function as enhancers or silencers.

1 citation

humanChIP-seq

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