Author

Nicholas Sweeney

The Ohio State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1 Assay:scRNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Greg Trevor SutherlandiD· 2 shared Hongjun FuiD· 2 shared Oscar HarariiD· 2 shared Ricardo D’Oliveira AlbanusiD· 2 shared Tae Yeon KimiD· 2 shared Abhirami Kannan IyeriD· 1 shared Ayslan Castro BrantiD· 1 shared Brenna C. NovotnyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersNeuroscience

Greg Trevor SutherlandORCID

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2 papers

Recent·Most cited

An end-to-end framework for single-cell-resolution, whole-transcriptomic spatial profiling in post-mortem human brain

Ayslan Castro Brant, Ekaterina Aladyeva, Hoang-Tuong Nguyen-Hao, Katharine W. Alltop, Nicholas Sweeney, Tae Yeon Kim, Iara Dantas de Souza, Subhodip Adhicary, Ricardo D’Oliveira Albanus, Krishna Bharani, Hongjun Fu, Gordon Meares, Greg Trevor Sutherland, Oscar Harari

This paper presents an end-to-end framework for single-cell whole-transcriptome spatial profiling of post-mortem human brain tissue, improving library quality and enabling cross-sample harmonization.

bioRxiv · Aug 1, 2026 · PreprintNeuroscience

Systematic analysis of cellular crosstalk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer's disease

Ricardo D’Oliveira Albanus, Gina M. Finan, Logan Brase, Nicholas Sweeney, Tae Yeon Kim, Shuo Chen, Yeonsu Ryoo, Joseph Park, Qi Guo, Abhirami Kannan Iyer, Mariana Acquarone, Shih‐Feng You, Brenna C. Novotny, Emily Margaret Mace, Patrícia Pereira, , Tae-Wan Kim

The paper investigates cell-to-cell communication in Alzheimer's disease to characterize disease biology and suggest new avenues for therapeutic intervention.

Science Translational Medicine · Jul 30, 2025Peer-reviewedNeuroscience