Author

Ekaterina Aladyeva

The Ohio State University Wexner Medical CenterORCID 0000-0002-3483-6944Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:clustering· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:deconvolution· 1 Research Focus:dimensionality reduction· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Maxim N. ArtyomoviD· 2 shared Alexey SerdyukoviD· 1 shared Anthony N. VomundiD· 1 shared Ayslan Castro BrantiD· 1 shared Cora D. ArthuriD· 1 shared Denis KleveroviD· 1 shared Derek J. TheiseniD· 1 shared Gordon Meares· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersImmunology

Maxim N. ArtyomovORCID

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3 papers

Recent·Most cited

Personalized Neoantigen Vaccines Synergize with Immune Checkpoint Therapy and CD8-Targeted Cytokines to Control B-Cell Lymphoma

Yuang Song, Ekaterina Aladyeva, Ruan F.V. Medrano, Derek J. Theisen, Cora D. Arthur, J. Michael White, Heather N. Kohlmiller, Anthony N. Vomund, Kartik Singhal, My Hoang, Samuel Ameh, Kathleen C. F. Sheehan, Ronald Levy, Todd A. Fehniger, Maxim N. Artyomov, , Robert D. Schreiber

This study shows that personalized neoantigen vaccines combined with immune checkpoint therapy and CD8-targeted cytokines effectively control B-cell lymphoma by enhancing T-cell responses and preventing dysfunction.

bioRxiv · Aug 6, 2026 · PreprintImmunology

An end-to-end framework for single-cell-resolution, whole-transcriptomic spatial profiling in post-mortem human brain

Ayslan Castro Brant, Ekaterina Aladyeva, Hoang-Tuong Nguyen-Hao, Katharine W. Alltop, Nicholas Sweeney, Tae Yeon Kim, Iara Dantas de Souza, Subhodip Adhicary, Ricardo D’Oliveira Albanus, Krishna Bharani, Hongjun Fu, Gordon Meares, Greg Trevor Sutherland, Oscar Harari

This paper presents an end-to-end framework for single-cell whole-transcriptome spatial profiling of post-mortem human brain tissue, improving library quality and enabling cross-sample harmonization.

bioRxiv · Aug 1, 2026 · PreprintNeuroscience

Non-negative matrix factorization and deconvolution as dual simplex problem

Denis Kleverov, Ekaterina Aladyeva, Alexey Serdyukov, Maxim N. Artyomov

This paper reformulates non-negative matrix factorization as a dual simplex problem, improving decomposition accuracy in both image and biological data.

Genome biology · Jan 14, 2026Peer-reviewedBioinformatics