Author

Nicole Attiq

University of California, Los Angeles

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Biophysics· 1

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Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Jing XueiD· 1 shared Michela OttoliaiD· 1 shared Scott JohniD· 1 shared Weizhong ZengiD· 1 shared Youxing JiangiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

Jing XueORCID

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1 paper

Recent·Most cited

Structural mechanisms of PIP2 activation and SEA0400 inhibition in human cardiac sodium-calcium exchanger NCX1

Jing Xue, Weizhong Zeng, Scott John, Nicole Attiq, Michela Ottolia, Youxing Jiang

This study presents cryo-EM structures of human NCX1 with PIP2 and SEA0400, revealing how these molecules modulate NCX1 activity through conformational changes.

bioRxiv · Dec 5, 2024Biophysics